IRON DEFICIENCY
and anemia
Iron: an Essential Nutrient, a Global Challenge
Iron is an essential mineral involved in numerous vital functions, including oxygen transport, energy production, DNA synthesis, and support for the immune system, muscles, and brain. Despite its magnitude, iron deficiency remains the most widespread nutritional deficiency worldwide, often silent but with significant effects such as fatigue, shortness of breath, and cognitive difficulties.
We address this still under-recognized need with innovative nutritional solutions designed to optimize iron absorption while respecting human physiology. Even a mild iron deficiency can have a profound impact and we are committed to making a difference.
The physiological innovation of Iron
The integration of new therapeutic strategies, based on innovative approaches, can significantly improve treatment adherence and ensure a more effective clinical response. In this context, tolfer™, a product based on IHAT™ (Iron Hydroxide Adipate Tartrate), represents true physiological innovation in the management of iron deficiency. IHAT™ is a ferritin analogue, designed to mimic the natural absorption mechanism of iron within the body, and thanks to this similarity, it offers an advanced option that combines both efficacy and tolerability. Moreover, IHAT™ is the first and only nanoparticle-based novel food approved by EFSA (EFSA Scientific Opinion n. 27/10/2021), recognized by the European Commission as a new source of iron (Commission Implementing Regulation (EU) 2022/1373 of 5/8/2022; Official Journal of the EU n. 2024/248). This recognition attests to its bioavailability and safety profile. Although effective, the currently available oral iron therapies could present tolerability limitations, with gastrointestinal side effects (such as nausea, constipation, diarrhea, and abdominal pain) that negatively affect patient adherence and, consequently, overall treatment effectiveness. These challenges represent a significant clinical issue, especially in more vulnerable patients, and require solutions that better balance absorption, efficacy, and tolerability while respecting the intestinal microbiota.
IHAT™ addresses this unmet need, offering a new perspective in iron deficiency, based on physiology and scientific innovation.
